Looking at a picture of Adam and Eve, the four year old noted that they weren't wearing any clothes. Now in our family, we have had to emphasize that certain body parts are rather germ-laden and should not be touched more than necessary (and I don't just mean fingers in noses). So looking at those unclothed people, the boy was a bit concerned.
"But mom, they aren't wearing any clothes. They'll get the Garden germy!"